#DIM SUPPLEMENT BREAST CANCER TRIAL#

The results of the study will also serve as an evaluation of the current use and success of preventive strategies for BRCA1 mutation carriers. This type of breast cancer is called estrogen receptor (ER). One of the indoles from cruciferous veggies is indole-3-carbinol or I3C.

#DIM SUPPLEMENT BREAST CANCER TRIAL#

The purpose of this study is to determine that there is a potential for oral DIM supplementation to result in the increased production of the BRCA1 protein in BRCA1 mutation carriers. DIM may prevent breast cancer 80 of breast cancers are caused by high levels of bad estrogen. Firestone conducted a human clinical trial of DIM and demonstrated that it increases the 2-hydroxylation of estrogen metabolites, a study that. Now lets talk about the compounds that may specifically influence breast cancer risk.

Women Reduced Risk of Breast Cancer, Optimize Your Estrogen Levels. The investigators think that DIM may increase the production of the normal copy of BRCA1 and offset the effect of the mutation. DIM Main Benefits Include: Super Antioxidant Promote Healthy Hormone Balance. It is also used to prevent an enlarged prostate (benign prostatic hypertrophy, BPH) and treat premenstrual syndrome (PMS). One dietary supplement that is thought to have potential for BRCA1 carriers is diindolylmethane (DIM), which is an active ingredient in broccoli and other green vegetables.ĭIM - is found in vegetables like broccoli and is available as a supplement in health food stores. Diindolylmethane is used for preventing breast, uterine, and colorectal cancer. Proponents claim that consuming Diindolylmethane will help to increase the protection against. The 2016 study in Nutrition Reviews showed that there is evidence supporting the notion of DIM playing a role in preventing breast cancer, as well as having therapeutic effects when taken during chemotherapy.

Condition or disease, Intervention/treatment, Phase. It is believed to be helpful in Breast Cancer treatment. Breast cancer: Because of the way DIM reacts with estrogen, its effects on estrogen-sensitive cancers has been studied.

The risk of breast and ovarian cancer in carriers of a BRCA1 mutation might be lowered by some nutritional supplements.įor example, green tea, broccoli and vitamin D are of potential interest. Because DIM has so many critical benefits for immunity, hormone balance and protection against hormone-related cancers, it’s a key ingredient in a powerful researched breast formula that I recommend in my clinical practice to support breast cancer treatment and prevention. DIM may slow the growth of tumor cells and be an effective treatment for breast cancer. Women with a BRCA1 mutation face a lifetime risk of breast cancer of approximately 70% and a lifetime risk of ovarian cancer of approximately 40%.Ī number of potential anti-cancer nutrients have been proposed, however, it is important that diet supplements be evaluated prior to general recommendation.

Dim supplement breast cancer